The spleen is an organ in the upper left portion of the abdomen, located beneath the diaphragm and under the ribs. It is part of the lymphatic system, and its main functions are to filter blood and help fight infection.


Lymphoma refers to a group of cancers arising from white blood cells (lymphocytes). Patients will often present with painless enlarged lymph nodes (lymphadenopathy), an enlarged spleen, fevers, night sweats, unintentional weight loss, or fatigue.